InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Anxa3

Summary

InnateDB Protein

IDBP-181901.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Anxa3

Protein Name

annexin A3

Synonyms

Anx3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031447

InnateDB Gene

IDBG-181899 (Anxa3)

Protein Structure

UniProt Annotation

Function

Inhibitor of phospholipase A2, also possesses anti- coagulant properties.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0019834	phospholipase A2 inhibitor activity
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0006909	phagocytosis
GO:0010595	positive regulation of endothelial cell migration
GO:0042742	defense response to bacterium
GO:0043086	negative regulation of catalytic activity
GO:0043312	neutrophil degranulation
GO:0045766	positive regulation of angiogenesis
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030670	phagocytic vesicle membrane
GO:0042581	specific granule
GO:0070062	extracellular vesicular exosome