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InnateDB Protein
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IDBP-182002.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gpr35
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Protein Name
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G protein-coupled receptor 35
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Synonyms
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KPG_007;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000027489
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InnateDB Gene
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IDBG-181998 (Gpr35)
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Protein Structure
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| Function |
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. {ECO:0000269PubMed:16754668}.
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| Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Predominantly expressed in immune and gastrointestinal tissues. {ECO:0000269PubMed:16754668}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
| Accession |
GO Term |
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GO:0004930
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G-protein coupled receptor activity
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| Biological Process |
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GO:0007186
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G-protein coupled receptor signaling pathway
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| Cellular Component |
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| PDB ID |
MGI:1929509
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| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like
IPR017452
GPCR, rhodopsin-like, 7TM
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| PFAM |
PF00001
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| PRINTS |
PR00237
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9ES90
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
64095
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| UniGene |
Mm.152780
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Gpr35
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AF200349
BC027429
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| GenPept |
AAG18487
AAH27429
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Version 5.4