InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bmp2k

Summary

InnateDB Protein

IDBP-182019.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bmp2k

Protein Name

BMP2 inducible kinase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037970

InnateDB Gene

IDBG-182017 (Bmp2k)

Protein Structure

UniProt Annotation

Function

May be involved in osteoblast differentiation.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed in spleen, kidney, lung, brain, heart, diaphragm and calvaria but not in liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0019208	phosphatase regulator activity

Biological Process

GO:0006468	protein phosphorylation
GO:0030500	regulation of bone mineralization
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:2155456

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt