Version 5.4
Mus musculus Protein: Csf2ra
Summary
InnateDB Protein IDBP-182100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Csf2ra
Protein Name colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Synonyms CD116; Csfgmra; GM-CSF-Ra; GM-CSFR;
Species Mus musculus
Ensembl Protein ENSMUSP00000075423
InnateDB Gene IDBG-182098 (Csf2ra)
Protein Structure
UniProt Annotation
Function Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
GO:0045471 response to ethanol
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1339754
InterPro IPR003961 Fibronectin, type III
IPR015321 Interleukin-6 receptor alpha, binding
PFAM PF00041
PF01108
PF09240
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q00941
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 12982
UniGene
RefSeq NP_034100
MGI ID
MGI Symbol Csf2ra
OMIM
CCDS CCDS29946
HPRD
IMGT
EMBL AC165327 M85078
GenPept AAA37421

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca