Version 5.4
Mus musculus Protein: Paqr3
Summary
InnateDB Protein IDBP-182134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Paqr3
Protein Name progestin and adipoQ receptor family member III
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000069324
InnateDB Gene IDBG-182132 (Paqr3)
Protein Structure
UniProt Annotation
Function Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi. {ECO:0000269PubMed:17724343}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:17724343}; Multi-pass membrane protein {ECO:0000269PubMed:17724343}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0010977 negative regulation of neuron projection development
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0034067 protein localization to Golgi apparatus
GO:0043407 negative regulation of MAP kinase activity
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2679683
InterPro IPR004254 Hly-III-related
PFAM PF03006
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6TCG8
PhosphoSite PhosphoSite-
TrEMBL Q4VAH2
UniProt Splice Variant
Entrez Gene 231474
UniGene Mm.332505
RefSeq NP_940814
MGI ID
MGI Symbol Paqr3
OMIM
CCDS CCDS19451
HPRD
IMGT
EMBL AY424292 BC096380 BC120853 BC120855 CH466529
GenPept AAH96380 AAI20854 AAI20856 AAR08380 EDL20346 EDL20348

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca