InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eif1ax

Summary

InnateDB Protein

IDBP-182260.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eif1ax

Protein Name

eukaryotic translation initiation factor 1A, X-linked

Synonyms

1500010B24Rik; AI426898; Eif1ay;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000084387

InnateDB Gene

IDBG-182258 (Eif1ax)

Protein Structure

UniProt Annotation

Function

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003743	translation initiation factor activity

Biological Process

GO:0006413

translational initiation

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1913485

InterPro

IPR001253 Translation initiation factor 1A (eIF-1A)
IPR006196 RNA-binding domain, S1, IF1 type
IPR012340 Nucleic acid-binding, OB-fold

PFAM

PF01176

PRINTS

PIRSF

SMART

SM00652

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BMJ3

PhosphoSite

PhosphoSite-Q8BMJ3

TrEMBL

UniProt Splice Variant

Entrez Gene

66235

UniGene

Mm.472009

RefSeq

NP_079713

MGI ID

MGI Symbol

Eif1ax

OMIM

CCDS

CCDS41192

HPRD

IMGT

EMBL

AK005185 AK007301 AK012233 AK012464 AK012714 AK021283 AK030774 AK031113 AK077710 AK090053 AK134827 AK134969 AK165574 AK166629 AK166852 BC027284

GenPept

AAH27284 BAB23869 BAB24942 BAB28110 BAB28259 BAB28428 BAB32361 BAC27130 BAC27259 BAC36971 BAC41069 BAE22301 BAE22363 BAE38266 BAE38904 BAE39071