Version 5.4
Mus musculus Protein: Cd37
Summary
InnateDB Protein IDBP-182315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd37
Protein Name CD37 antigen
Synonyms Tspan26;
Species Mus musculus
Ensembl Protein ENSMUSP00000096061
InnateDB Gene IDBG-182311 (Cd37)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002639 positive regulation of immunoglobulin production
GO:0002920 regulation of humoral immune response
GO:0008285 negative regulation of cell proliferation
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0042832 defense response to protozoan
GO:0050688 regulation of defense response to virus
Cellular Component
GO:0001772 immunological synapse
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88330
InterPro IPR000301 Tetraspanin
IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS PR00259
PIRSF PIRSF002419
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61470
PhosphoSite PhosphoSite-Q61470
TrEMBL Q4FK35
UniProt Splice Variant
Entrez Gene 12493
UniGene Mm.3689
RefSeq NP_031671
MGI ID
MGI Symbol Cd37
OMIM
CCDS CCDS21237
HPRD
IMGT
EMBL AK155966 BC019402 CH466603 CT010217 U18367 U18368 U18369 U18370 U18371 U18372
GenPept AAB39500 AAH19402 BAE33526 CAJ18425 EDL22833

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca