Version 5.4
Mus musculus Protein: Sltm
Summary
InnateDB Protein IDBP-182335.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sltm
Protein Name SAFB-like, transcription modulator
Synonyms 5730455C01Rik; 5730555F13Rik; 9130215G10Rik; Met;
Species Mus musculus
Ensembl Protein ENSMUSP00000049112
InnateDB Gene IDBG-182331 (Sltm)
Protein Structure
UniProt Annotation
Function When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis. {ECO:0000269PubMed:17630952}.
Subcellular Localization Nucleus {ECO:0000269PubMed:17630952}. Note=Detected in punctate structures.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1913910
InterPro IPR000504 RNA recognition motif domain
IPR003034 SAP domain
PFAM PF00076
PF02037
PRINTS
PIRSF
SMART SM00360
SM00513
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CH25
PhosphoSite PhosphoSite-Q8CH25
TrEMBL B9EI57
UniProt Splice Variant
Entrez Gene 66660
UniGene Mm.420872
RefSeq NP_080613
MGI ID
MGI Symbol Sltm
OMIM
CCDS CCDS23322
HPRD
IMGT
EMBL AF462146 AK017839 AK045723 AK077578 AK134756 BC019992 BC139202 CH466522
GenPept AAH19992 AAI39203 AAO15605 BAB30967 BAC32471 BAC36873 BAE22267 EDL26202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca