Version 5.4
Mus musculus Protein: Aqp12
Summary
InnateDB Protein IDBP-182414.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp12
Protein Name aquaporin 12
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000060622
InnateDB Gene IDBG-182412 (Aqp12)
Protein Structure
UniProt Annotation
Function Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Restricted to pancreatic acinar cells. {ECO:0000269PubMed:15809071}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2664636
InterPro IPR000425 Major intrinsic protein
IPR016697 Aquaporin 11/12
IPR023265 Aquaporin 12
IPR023271 Aquaporin-like
PFAM PF00230
PRINTS PR00783
PR02025
PIRSF PIRSF017529
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CHJ2
PhosphoSite PhosphoSite-
TrEMBL Q3V2I1
UniProt Splice Variant
Entrez Gene 208760
UniGene Mm.235537
RefSeq NP_808255
MGI ID
MGI Symbol Aqp12
OMIM
CCDS CCDS15183
HPRD
IMGT
EMBL AB084104 AK131815 BC107212 BC107213
GenPept AAI07213 AAI07214 BAC45227 BAE20816

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca