Version 5.4
Mus musculus Protein: Dcp1b
Summary
InnateDB Protein IDBP-182425.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dcp1b
Protein Name DCP1 decapping enzyme homolog b (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000073568
InnateDB Gene IDBG-182423 (Dcp1b)
Protein Structure
UniProt Annotation
Function May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016787 hydrolase activity
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2442404
InterPro IPR010334 Dcp1-like decapping
PFAM PF06058
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U564
PhosphoSite PhosphoSite-Q3U564
TrEMBL
UniProt Splice Variant
Entrez Gene 319618
UniGene Mm.395269
RefSeq
MGI ID
MGI Symbol Dcp1b
OMIM
CCDS
HPRD
IMGT
EMBL AK050548 AK153860 BC141163
GenPept AAI41164 BAE20676 BAE32216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca