Version 5.4
Mus musculus Protein: Prkg2
Summary
InnateDB Protein IDBP-182437.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prkg2
Protein Name protein kinase, cGMP-dependent, type II
Synonyms AW212535; cGK-II; CGKII; Prkgr2;
Species Mus musculus
Ensembl Protein ENSMUSP00000031277
InnateDB Gene IDBG-182435 (Prkg2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004692 cGMP-dependent protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030553 cGMP binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007623 circadian rhythm
GO:0032922 circadian regulation of gene expression
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:108173
InterPro IPR000595 Cyclic nucleotide-binding domain
IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR002373 cAMP/cGMP-dependent protein kinase
IPR002374 cGMP-dependent kinase
IPR011009 Protein kinase-like domain
IPR016232 cGMP-dependent protein kinase
IPR018490 Cyclic nucleotide-binding-like
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00027
PF00069
PF07714
PRINTS PR00109
PR00103
PR00104
PIRSF PIRSF000559
SMART SM00100
SM00133
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3TMJ2
UniProt Splice Variant
Entrez Gene 19092
UniGene Mm.263002
RefSeq
MGI ID
MGI Symbol Prkg2
OMIM
CCDS
HPRD
IMGT
EMBL AC141896 AK165904
GenPept BAE38450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca