InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Naa16

Summary

InnateDB Protein

IDBP-182599.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Naa16

Protein Name

N(alpha)-acetyltransferase 16, NatA auxiliary subunit

Synonyms

1300019C06Rik; Narg1l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022597

InnateDB Gene

IDBG-182597 (Naa16)

Protein Structure

UniProt Annotation

Function

Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Highest levels in the kidney and testes. Moderate expression in the liver, thymus and skin. {ECO:0000269PubMed:12888564}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004596	peptide alpha-N-acetyltransferase activity
GO:0005515	protein binding
GO:0043022	ribosome binding

Biological Process

GO:0043066	negative regulation of apoptotic process
GO:0050821	protein stabilization

Cellular Component

GO:0031415	NatA complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1914147

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat
IPR021183 N-terminal acetyltransferase A, auxiliary subunit

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181
PF12569

PRINTS

PIRSF

PIRSF000422

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt