Version 5.4
Mus musculus Protein: Mtrf1
Summary
InnateDB Protein IDBP-182693.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtrf1
Protein Name mitochondrial translational release factor 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000022600
InnateDB Gene IDBG-182691 (Mtrf1)
Protein Structure
UniProt Annotation
Function Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA. {ECO:0000250}.
Subcellular Localization Mitochondrion.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:2384815
InterPro IPR000352 Peptide chain release factor class I/class II
IPR005139 Peptide chain release factor
PFAM PF00472
PF03462
PRINTS
PIRSF
SMART SM00937
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K126
PhosphoSite PhosphoSite-Q8K126
TrEMBL
UniProt Splice Variant
Entrez Gene 211253
UniGene
RefSeq NP_666072
MGI ID
MGI Symbol Mtrf1
OMIM
CCDS CCDS27297
HPRD
IMGT
EMBL AK043981 BC028898
GenPept AAH28898 BAC31724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca