Version 5.4
| Mus musculus Protein: Fbxl14 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-182728.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Fbxl14 | ||||||
| Protein Name | F-box and leucine-rich repeat protein 14 | ||||||
| Synonyms | AW322056; Fbx14l; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000032094 | ||||||
| InnateDB Gene | IDBG-182726 (Fbxl14) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Substrate-recognition component of some (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1 (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:2141676 | ||||||
| InterPro |
IPR001611
Leucine-rich repeat IPR001810 F-box domain IPR006553 Leucine-rich repeat, cysteine-containing subtype IPR013101 Leucine-rich repeat 2 |
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| PFAM |
PF00560
PF13504 PF13855 PF00646 PF12937 PF13013 PF07723 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00256
SM00367 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q8BID8 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 101358 | ||||||
| UniGene | Mm.448356 | ||||||
| RefSeq | NP_598701 | ||||||
| MGI ID | |||||||
| MGI Symbol | Fbxl14 | ||||||
| OMIM | |||||||
| CCDS | CCDS20475 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AF467463 AK084506 AK155154 BC006913 BC021329 | ||||||
| GenPept | AAH06913 AAH21329 AAL75967 BAC39201 BAE33081 | ||||||