Version 5.4
Mus musculus Protein: Rnf112
Summary
InnateDB Protein IDBP-182832.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf112
Protein Name ring finger protein 112
Synonyms bfp; Zfp179; ZNF179;
Species Mus musculus
Ensembl Protein ENSMUSP00000056464
InnateDB Gene IDBG-182826 (Rnf112)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:9806830}. Nucleus {ECO:0000269PubMed:9806830}. Note=Predominantly in the nucleus, but some amounts were also found in the cytoplasm.
Disease Associations
Tissue Specificity Expressed in neural cells of the cerebral cortex, hippocampus, lateral amygdaloid nucleus, and ventromedial hypothalamus. Also expressed strongly in the marginal zone of brain vesicles, optic stalk, and cartilage primordium. {ECO:0000269PubMed:9806830}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
Biological Process
GO:0006184 GTP catabolic process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:106611
InterPro IPR001841 Zinc finger, RING-type
IPR015894 Guanylate-binding protein, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF13639
PF14634
PF02263
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96DY5
PhosphoSite PhosphoSite-Q96DY5
TrEMBL
UniProt Splice Variant
Entrez Gene 22671
UniGene
RefSeq NP_033574
MGI ID
MGI Symbol Rnf112
OMIM
CCDS CCDS24812
HPRD
IMGT
EMBL AB013097 AK165038 AL604029 BC013139 BC037118
GenPept AAH13139 AAH37118 BAA34180 BAE38012 CAI24177 CAI24178 CAI24179

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca