Version 5.4
Mus musculus Protein: Ntf5
Summary
InnateDB Protein IDBP-182939.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ntf5
Protein Name neurotrophin 5
Synonyms 2900040K06Rik; AI462899; NT-4; NT4; NT4/5; Ntf-5; Ntf4;
Species Mus musculus
Ensembl Protein ENSMUSP00000057916
InnateDB Gene IDBG-182937 (Ntf5)
Protein Structure
UniProt Annotation
Function Could serve as a target-derived trophic factor for sensory and sympathetic neurons. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005166 neurotrophin p75 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0007402 ganglion mother cell fate determination
GO:0007616 long-term memory
GO:0008052 sensory organ boundary specification
GO:0008344 adult locomotory behavior
GO:0008544 epidermis development
GO:0042490 mechanoreceptor differentiation
GO:0060384 innervation
GO:0060548 negative regulation of cell death
GO:0061193 taste bud development
Cellular Component
GO:0005576 extracellular region
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:97381
InterPro IPR002072 Nerve growth factor-related
IPR020408 Nerve growth factor-like
IPR020432 Neurotrophin-4
IPR029034 Cystine-knot cytokine
PFAM PF00243
PRINTS PR00268
PR01915
PIRSF PIRSF001789
SMART SM00140
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80VU4
PhosphoSite PhosphoSite-
TrEMBL S5MI68
UniProt Splice Variant
Entrez Gene 78405
UniGene Mm.20344
RefSeq NP_937833
MGI ID
MGI Symbol Ntf5
OMIM
CCDS CCDS21241
HPRD
IMGT
EMBL BC052191 KC855564
GenPept AAH52191 AGR50955

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca