InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sugt1

Summary

InnateDB Protein

IDBP-182951.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sugt1

Protein Name

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

Synonyms

2410174K12Rik; SGT1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000052942

InnateDB Gene

IDBG-182949 (Sugt1)

Protein Structure

UniProt Annotation

Function

May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates the to nucleus upon heat shock, requiring S100A6. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	48 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1915205

InterPro

IPR001440 Tetratricopeptide TPR1
IPR007052 CS domain
IPR007699 SGS
IPR008978 HSP20-like chaperone
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM