Version 5.4
Mus musculus Protein: Ppp1r7
Summary
InnateDB Protein IDBP-183009.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppp1r7
Protein Name protein phosphatase 1, regulatory (inhibitor) subunit 7
Synonyms 2310014J01Rik; SDS22;
Species Mus musculus
Ensembl Protein ENSMUSP00000027494
InnateDB Gene IDBG-183005 (Ppp1r7)
Protein Structure
UniProt Annotation
Function Regulatory subunit of protein phosphatase 1. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed with high level in testis. Expression increases during puberty. Expressed in spermatids and probably also in spermatozoa. {ECO:0000269PubMed:12972598}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035307 positive regulation of protein dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1913635
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003603 U2A\'/phosphoprotein 32 family A, C-terminal
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
SM00446
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UM45
PhosphoSite PhosphoSite-Q3UM45
TrEMBL
UniProt Splice Variant
Entrez Gene 66385
UniGene Mm.88704
RefSeq NP_075689
MGI ID
MGI Symbol Ppp1r7
OMIM
CCDS CCDS15187
HPRD
IMGT
EMBL AF067129 AF222867 AK009870 AK145136 AK162517 BC013524
GenPept AAH13524 AAK00624 AAK08624 BAB26554 BAE26253 BAE36954

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca