InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rs1

Summary

InnateDB Protein

IDBP-183120.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rs1

Protein Name

retinoschisis (X-linked, juvenile) 1 (human)

Synonyms

Rs1h; tmgc1; Xlrs1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033650

InnateDB Gene

IDBG-183118 (Rs1)

Protein Structure

UniProt Annotation

Function

May be active in cell adhesion processes during retinal development. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Restricted to the retina. At the mRNA level, detected only within the photoreceptor cell layer, most prominently within the inner segments of the photoreceptors. Undetectable in the inner plexiform layers and the inner nuclear layer. At the protein level, found in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer (at protein level). {ECO:0000269PubMed:10915776}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001786	phosphatidylserine binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0010314	phosphatidylinositol-5-phosphate binding
GO:0032266	phosphatidylinositol-3-phosphate binding
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
GO:0070273	phosphatidylinositol-4-phosphate binding
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding