Version 5.4
Homo sapiens Protein: CLEC1B
Summary
InnateDB Protein IDBP-18313.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC1B
Protein Name C-type lectin domain family 1, member B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000327169
InnateDB Gene IDBG-18309 (CLEC1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. {ECO:0000269PubMed:10671229, ECO:0000269PubMed:16174766, ECO:0000269PubMed:16940507}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P126
PhosphoSite PhosphoSite-Q9P126
TrEMBL
UniProt Splice Variant
Entrez Gene 51266
UniGene Hs.409794
RefSeq NP_001092901
HUGO HGNC:24356
OMIM 606783
CCDS CCDS41751
HPRD 09490
IMGT
EMBL AC091814 AF124841 AY358599 BC029554
GenPept AAF36777 AAH29554 AAQ88962

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca