Version 5.4
| Mus musculus Protein: Crisp1 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-183163.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | Crisp1 | ||||
| Protein Name | cysteine-rich secretory protein 1 | ||||
| Synonyms | Aeg1; AW324342; CRISP-1; | ||||
| Species | Mus musculus | ||||
| Ensembl Protein | ENSMUSP00000026498 | ||||
| InnateDB Gene | IDBG-183161 (Crisp1) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens. | ||||
| Subcellular Localization | Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory granules of granular convoluted tubules cells. | ||||
| Disease Associations | |||||
| Tissue Specificity | Mainly found in the cauda epididymis where it is synthesized by the principal cells and secreted into the lumen. Binds to the heads of spermatozoa. Also expressed in the submandibular gland. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | MGI:102553 | ||||
| InterPro |
IPR001283
Cysteine-rich secretory protein, allergen V5/Tpx-1-related IPR013871 Cysteine-rich secretory protein IPR014044 CAP domain |
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| PFAM |
PF08562
PF00188 |
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| PRINTS |
PR00837
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| PIRSF |
PIRSF038921
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| SMART |
SM00198
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q03401 | ||||
| PhosphoSite | PhosphoSite-Q03401 | ||||
| TrEMBL | Q545H0 | ||||
| UniProt Splice Variant | |||||
| Entrez Gene | 11571 | ||||
| UniGene | Mm.470588 | ||||
| RefSeq | NP_033768 | ||||
| MGI ID | |||||
| MGI Symbol | Crisp1 | ||||
| OMIM | |||||
| CCDS | CCDS28784 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AK009449 CH466559 L05559 M92849 | ||||
| GenPept | AAA37185 AAA37460 BAB26295 EDL23383 | ||||