Version 5.4
Mus musculus Protein: Ppcs
Summary
InnateDB Protein IDBP-183166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppcs
Protein Name phosphopantothenoylcysteine synthetase
Synonyms 6330579B17Rik; AI413471; AI790434;
Species Mus musculus
Ensembl Protein ENSMUSP00000030385
InnateDB Gene IDBG-183164 (Ppcs)
Protein Structure
UniProt Annotation
Function Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004632 phosphopantothenate--cysteine ligase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1915237
InterPro IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal
PFAM PF04127
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VDG5
PhosphoSite PhosphoSite-Q8VDG5
TrEMBL
UniProt Splice Variant
Entrez Gene 106564
UniGene Mm.426857
RefSeq NP_080770
MGI ID
MGI Symbol Ppcs
OMIM
CCDS CCDS18581
HPRD
IMGT
EMBL AK006290 AK159952 BC021894
GenPept AAH21894 BAB24509 BAE35508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca