Version 5.4
Homo sapiens Protein: PDILT
Summary
InnateDB Protein IDBP-18319.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDILT
Protein Name protein disulfide isomerase-like, testis expressed
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000305465
InnateDB Gene IDBG-18317 (PDILT)
Protein Structure
UniProt Annotation
Function Probable redox-inactive chaperone involved in spermatogenesis. {ECO:0000269PubMed:17507649}.
Subcellular Localization Endoplasmic reticulum {ECO:0000255PROSITE- ProRule:PRU10138, ECO:0000269PubMed:15475357}.
Disease Associations
Tissue Specificity Testis-specific. {ECO:0000269PubMed:15475357, ECO:0000269PubMed:17507649}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0031545 peptidyl-proline 4-dioxygenase activity
Biological Process
GO:0006457 protein folding
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0016477 cell migration
GO:0030154 cell differentiation
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
PFAM PF13098
PF13192
PF13462
PF13905
PF00085
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N807
PhosphoSite PhosphoSite-Q8N807
TrEMBL
UniProt Splice Variant
Entrez Gene 204474
UniGene Hs.376025
RefSeq NP_777584
HUGO HGNC:27338
OMIM
CCDS CCDS10584
HPRD 15111
IMGT
EMBL AK097476 BC042607 BC044936 CH471186
GenPept AAH42607 AAH44936 BAC05068 EAW50316

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca