Mus musculus Protein: Gja6
Summary
InnateDB Protein IDBP-183215.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gja6
Protein Name gap junction protein, alpha 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000069187
InnateDB Gene IDBG-183213 (Gja6)
Protein Structure
UniProt Annotation
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005243 gap junction channel activity
Biological Process
GO:0007165 signal transduction
GO:0010644 cell communication by electrical coupling
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0055085 transmembrane transport
Cellular Component
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95717
InterPro IPR000500 Connexin
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6S5G4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 414089
UniGene Mm.404132
RefSeq NP_001001496
MGI ID
MGI Symbol Gja6
OMIM
CCDS CCDS30506
HPRD
IMGT
EMBL AK040693 AK146838 AK168953 AL669939 AL670462 AY465183 BC117760 CH466571 CR478402
GenPept AAI17761 AAR28037 BAC30669 BAE27472 BAE40759 CAM17695 EDL40800