Version 5.4
Mus musculus Protein: Ccdc53
Summary
InnateDB Protein IDBP-183238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccdc53
Protein Name coiled-coil domain containing 53
Synonyms 2900091E11Rik; 5730495F03Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000020248
InnateDB Gene IDBG-183236 (Ccdc53)
Protein Structure
UniProt Annotation
Function Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0015629 actin cytoskeleton
GO:0043231 intracellular membrane-bounded organelle
GO:0071203 WASH complex
Protein Structure and Domains
PDB ID MGI:1914532
InterPro IPR019309 WASH complex, subunit CCDC53
PFAM PF10152
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CR27
PhosphoSite PhosphoSite-Q9CR27
TrEMBL S4R1K7
UniProt Splice Variant
Entrez Gene 67282
UniGene Mm.473901
RefSeq NP_080346
MGI ID
MGI Symbol Ccdc53
OMIM
CCDS CCDS24108
HPRD
IMGT
EMBL AC168315 AK004206 AK009358 AK013835 AK158822 BC029256
GenPept AAH29256 BAB23220 BAB26239 BAB29011 BAE34682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca