Version 5.4
Mus musculus Protein: Bcdin3d
Summary
InnateDB Protein IDBP-183279.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcdin3d
Protein Name BCDIN3 domain containing
Synonyms 4930556P03Rik; AV138748;
Species Mus musculus
Ensembl Protein ENSMUSP00000041809
InnateDB Gene IDBG-183277 (Bcdin3d)
Protein Structure
UniProt Annotation
Function O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0001510 RNA methylation
GO:0010586 miRNA metabolic process
GO:2000632 negative regulation of pre-miRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1922534
InterPro IPR010675 Bicoid-interacting 3
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF06859
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91YP1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75284
UniGene Mm.32826
RefSeq NP_083512
MGI ID
MGI Symbol Bcdin3d
OMIM
CCDS CCDS37202
HPRD
IMGT
EMBL AK016154 BC016225
GenPept AAH16225 BAB30128

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca