InnateDB Protein
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IDBP-183307.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dram1
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Protein Name
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DNA-damage regulated autophagy modulator 1
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Synonyms
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1200002N14Rik; Dram;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000020249
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InnateDB Gene
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IDBG-183305 (Dram1)
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Protein Structure
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Function |
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy (By similarity). {ECO:0000250}.
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Subcellular Localization |
Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1918962
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InterPro |
IPR019402
Frag1/DRAM/Sfk1
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PFAM |
PF10277
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9DC58
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3Z5R7
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UniProt Splice Variant |
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Entrez Gene |
71712
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UniGene |
Mm.394663
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RefSeq |
NP_082154
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MGI ID |
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MGI Symbol |
Dram1
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OMIM |
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CCDS |
CCDS24109
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HPRD |
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IMGT |
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EMBL |
AC125486
AK004552
BC021433
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GenPept |
AAH21433
BAB23366
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