InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Helq

Summary

InnateDB Protein

IDBP-183474.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Helq

Protein Name

helicase, POLQ-like

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041599

InnateDB Gene

IDBG-183472 (Helq)

Protein Structure

UniProt Annotation

Function

DNA-dependent ATPase and 5' to 3' DNA helicase.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006259	DNA metabolic process
GO:0032508	DNA duplex unwinding

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0017117	single-stranded DNA-dependent ATP-dependent DNA helicase complex

Protein Structure and Domains

PDB ID

MGI:2176740

InterPro

IPR001650 Helicase, C-terminal
IPR006935 Helicase/UvrB domain
IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04851
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2VPA6