Version 5.4
Mus musculus Protein: Prpsap2
Summary
InnateDB Protein IDBP-183630.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prpsap2
Protein Name phosphoribosyl pyrophosphate synthetase-associated protein 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000004955
InnateDB Gene IDBG-183628 (Prpsap2)
Protein Structure
UniProt Annotation
Function Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003674 molecular_function
GO:0004749 ribose phosphate diphosphokinase activity
Biological Process
GO:0009165 nucleotide biosynthetic process
GO:0060348 bone development
Cellular Component
GO:0002189 ribose phosphate diphosphokinase complex
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:2384838
InterPro IPR005946 Ribose-phosphate diphosphokinase
IPR029057 Phosphoribosyltransferase-like
PFAM PF14572
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R574
PhosphoSite PhosphoSite-Q8R574
TrEMBL Q5SWZ0
UniProt Splice Variant
Entrez Gene 212627
UniGene Mm.400631
RefSeq NP_659055
MGI ID
MGI Symbol Prpsap2
OMIM
CCDS CCDS24819
HPRD
IMGT
EMBL AK038680 AK076811 BC023178 BC051438 BC106185
GenPept AAH23178 AAH51438 AAI06186 BAC30096 BAC36491

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca