Version 5.4
Homo sapiens Protein: CLEC1A
Summary
InnateDB Protein IDBP-18402.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC1A
Protein Name C-type lectin domain family 1, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000326407
InnateDB Gene IDBG-18400 (CLEC1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed preferentially in dendritic cells. {ECO:0000269PubMed:10671229}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0030246 carbohydrate binding
Biological Process
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NC01
PhosphoSite PhosphoSite-
TrEMBL F8WCT4
UniProt Splice Variant
Entrez Gene 51267
UniGene Hs.29549
RefSeq NP_057595
HUGO HGNC:24355
OMIM 606782
CCDS CCDS8612
HPRD 09489
IMGT
EMBL AC024224 AF200949 AK075114 AY358587 BC039072 BC067746
GenPept AAF36830 AAH39072 AAH67746 AAQ88950 BAC11410

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca