Version 5.4
Mus musculus Protein: Gins3
Summary
InnateDB Protein IDBP-184034.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gins3
Protein Name GINS complex subunit 3 (Psf3 homolog)
Synonyms 2700085M18Rik; AI616142;
Species Mus musculus
Ensembl Protein ENSMUSP00000034094
InnateDB Gene IDBG-184032 (Gins3)
Protein Structure
UniProt Annotation
Function The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1926083
InterPro IPR021151 GINS complex
PFAM PF05916
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CY94
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 78833
UniGene Mm.35546
RefSeq NP_084474
MGI ID
MGI Symbol Gins3
OMIM
CCDS CCDS22564
HPRD
IMGT
EMBL AK019225 AK146574 AK150602 AK151243 AK152572 AK160606 BC039794 BC064746
GenPept AAH39794 AAH64746 BAB31610 BAE27270 BAE29694 BAE30235 BAE31324 BAE35909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca