InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pigb

Summary

InnateDB Protein

IDBP-184138.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pigb

Protein Name

phosphatidylinositol glycan anchor biosynthesis, class B

Synonyms

Pig-b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096165

InnateDB Gene

IDBG-253727 (Pigb)

Protein Structure

UniProt Annotation

Function

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016757	transferase activity, transferring glycosyl groups

Biological Process

GO:0006505	GPI anchor metabolic process
GO:0006506	GPI anchor biosynthetic process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1891825

InterPro

IPR005599 GPI mannosyltransferase

PFAM

PF03901

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JJQ0

PhosphoSite

PhosphoSite-Q9JJQ0

TrEMBL

UniProt Splice Variant

Entrez Gene

55981

UniGene

RefSeq

NP_061377

MGI ID

MGI Symbol

Pigb

OMIM

CCDS

CCDS40687

HPRD

IMGT

EMBL

AK153819 BC052658 D84436

GenPept

AAH52658 BAA94827 BAE32195