Mus musculus Protein: Grpr
Summary
InnateDB Protein IDBP-184193.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grpr
Protein Name gastrin releasing peptide receptor
Synonyms GRP-R;
Species Mus musculus
Ensembl Protein ENSMUSP00000033730
InnateDB Gene IDBG-184191 (Grpr)
Protein Structure
UniProt Annotation
Function Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Brain (hypothalamus), pancreatic acinar cells, and fibroblasts.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004946 bombesin receptor activity
GO:0005515 protein binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0031989 bombesin receptor signaling pathway
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95836
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000611 Neuropeptide Y receptor family
IPR001556 Bombesin receptor
IPR001966 Gastrin-releasing peptide receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
PFAM PF00001
PF10320
PF10323
PRINTS PR00237
PR01012
PR00358
PR00640
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21729
PhosphoSite PhosphoSite-
TrEMBL Q53WV4
UniProt Splice Variant
Entrez Gene 14829
UniGene Mm.4687
RefSeq NP_032203
MGI ID
MGI Symbol Grpr
OMIM
CCDS CCDS30512
HPRD
IMGT
EMBL AK033473 BC113145 CH466571 M57922 M61000 U84263 U84264 U84265
GenPept AAA37744 AAA75650 AAD00557 AAI13146 BAC28307 EDL40772