Version 5.4
| Mus musculus Protein: Setd6 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-184196.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Setd6 | ||||||||
| Protein Name | SET domain containing 6 | ||||||||
| Synonyms | 0610039J04Rik; 3110004G14Rik; AI413388; C76402; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000034096 | ||||||||
| InnateDB Gene | IDBG-184194 (Setd6) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1913333 | ||||||||
| InterPro |
IPR001214
SET domain IPR011383 RuBisCO-cytochrome methylase, RMS1 IPR015353 Rubisco LSMT, substrate-binding domain |
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| PFAM |
PF00856
PF09273 |
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| PRINTS | |||||||||
| PIRSF |
PIRSF011771
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| SMART |
SM00317
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9CWY3 | ||||||||
| PhosphoSite | PhosphoSite-Q9CWY3 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 66083 | ||||||||
| UniGene | Mm.261321 | ||||||||
| RefSeq | NP_001030295 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Setd6 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22566 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK010304 AK075597 AK167753 BC139198 BC139199 CH466525 | ||||||||
| GenPept | AAI39199 AAI39200 BAB26837 BAC35846 BAE39788 EDL11181 | ||||||||