Version 5.4
| Mus musculus Protein: Dennd2d | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-184616.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Dennd2d | ||||||
| Protein Name | DENN/MADD domain containing 2D | ||||||
| Synonyms | 2010308M01Rik; AI451421; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000029508 | ||||||
| InnateDB Gene | IDBG-184614 (Dennd2d) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:2181193 | ||||||
| InterPro |
IPR001194
DENN domain IPR005112 dDENN domain IPR005113 uDENN domain |
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| PFAM |
PF02141
PF03455 PF03456 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00799
SM00801 SM00800 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q91VV4 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 72121 | ||||||
| UniGene | Mm.14816 | ||||||
| RefSeq | NP_001265870 | ||||||
| MGI ID | |||||||
| MGI Symbol | Dennd2d | ||||||
| OMIM | |||||||
| CCDS | CCDS51040 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK008546 AK157279 BC008266 BC043727 | ||||||
| GenPept | AAH08266 AAH43727 BAB25733 BAE34027 | ||||||