Version 5.4
Mus musculus Protein: Letmd1
Summary
InnateDB Protein IDBP-184662.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Letmd1
Protein Name LETM1 domain containing 1
Synonyms 1110019O13Rik; AI593524; BB130465; BB235638; HCCR-2; HCCR1; MCC-32; Mccr;
Species Mus musculus
Ensembl Protein ENSMUSP00000037546
InnateDB Gene IDBG-184660 (Letmd1)
Protein Structure
UniProt Annotation
Function Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. {ECO:0000269PubMed:12879013}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1915864
InterPro IPR002477 Peptidoglycan binding-like
IPR011685 LETM1-like
PFAM PF01471
PF07766
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q924L1
PhosphoSite PhosphoSite-Q924L1
TrEMBL
UniProt Splice Variant
Entrez Gene 68614
UniGene
RefSeq NP_598854
MGI ID
MGI Symbol Letmd1
OMIM
CCDS CCDS27838
HPRD
IMGT
EMBL AF287293 AF401483 AK045256 AK080221 AK154676 AK169341 BC021361
GenPept AAH21361 AAK83032 AAM90666 BAC32283 BAC37851 BAE32758 BAE41093

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca