InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptpn13

Summary

InnateDB Protein

IDBP-184673.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ptpn13

Protein Name

protein tyrosine phosphatase, non-receptor type 13

Synonyms

AI324989; PTP-BL; PTPL1; Ptpri; RIP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048119

InnateDB Gene

IDBG-184669 (Ptpn13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0030027	lamellipodium
GO:0043005	neuron projection
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:103293

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000299 FERM domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR001478 PDZ domain
IPR003100 Argonaute/Dicer protein, PAZ domain
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR011019 KIND
IPR012153 Protein-tyrosine phosphatase, non-receptor type-13
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029021 Protein-tyrosine phosphatase-like
IPR029071 Ubiquitin-related domain

PFAM