Homo sapiens Protein: ACSM2B
Summary
InnateDB Protein IDBP-18471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACSM2B
Protein Name acyl-CoA synthetase medium-chain family member 2B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000327453
InnateDB Gene IDBG-18411 (ACSM2B)
Protein Structure
UniProt Annotation
Function Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro). {ECO:0000269PubMed:12616642}.
Subcellular Localization Mitochondrion matrix {ECO:0000269PubMed:10434065, ECO:0000269PubMed:12616642, ECO:0000269PubMed:19634011}.
Disease Associations
Tissue Specificity Detected in liver. {ECO:0000269PubMed:10434065, ECO:0000269PubMed:19634011}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0047760 butyrate-CoA ligase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID
InterPro IPR000873 AMP-dependent synthetase/ligase
PFAM PF00501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q68CK6
PhosphoSite PhosphoSite-Q68CK6
TrEMBL H3BTX9
UniProt Splice Variant
Entrez Gene 348158
UniGene Hs.670434
RefSeq NP_001098539
HUGO HGNC:30931
OMIM 614359
CCDS CCDS10586
HPRD 17124
IMGT
EMBL AB073604 AC141053 AC141273 AY160217
GenPept AAO17576 BAD38642