InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Csrnp2

Summary

InnateDB Protein

IDBP-184733.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Csrnp2

Protein Name

cysteine-serine-rich nuclear protein 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000052144

InnateDB Gene

IDBG-184731 (Csrnp2)

Protein Structure

UniProt Annotation

Function

Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May play a role in apoptosis. {ECO:0000269PubMed:17726538}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:17726538}.

Disease Associations

Tissue Specificity

Highest expression detected in thymus, brain and ovary. Low levels detected in naive T-cells. {ECO:0000269PubMed:17726538}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0019902	phosphatase binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006915	apoptotic process
GO:0010923	negative regulation of phosphatase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter