Version 5.4
Mus musculus Protein: Pigl
Summary
InnateDB Protein IDBP-184970.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigl
Protein Name phosphatidylinositol glycan anchor biosynthesis, class L
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000014389
InnateDB Gene IDBG-184968 (Pigl)
Protein Structure
UniProt Annotation
Function Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2681271
InterPro IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related
IPR024078 Putative deacetylase LmbE-like domain
PFAM PF02585
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SX19
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 327942
UniGene
RefSeq NP_001034625
MGI ID
MGI Symbol Pigl
OMIM
CCDS CCDS24824
HPRD
IMGT
EMBL AK158149 AL596181 BX248411 BX470084
GenPept BAE34385 CAI24059 CAI24669 CAI24686

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca