InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cela1

Summary

InnateDB Protein

IDBP-185037.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cela1

Protein Name

chymotrypsin-like elastase family, member 1

Synonyms

1810009A17Rik; 1810062B19Rik; Ela-1; Ela1; PC-TsF;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023775

InnateDB Gene

IDBG-185035 (Cela1)

Protein Structure

UniProt Annotation

Function

Acts upon elastin. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006508	proteolysis
GO:0006954	inflammatory response
GO:0009791	post-embryonic development
GO:0016055	Wnt signaling pathway
GO:0031017	exocrine pancreas development
GO:0035264	multicellular organism growth
GO:0042127	regulation of cell proliferation
GO:0045595	regulation of cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055123	digestive system development
GO:0061113	pancreas morphogenesis