InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bcl2l10

Summary

InnateDB Protein

IDBP-185090.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bcl2l10

Protein Name

Bcl2-like 10

Synonyms

AA420380; AU023065; Boo; C85687; Diva;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034709

InnateDB Gene

IDBG-185088 (Bcl2l10)

Protein Structure

UniProt Annotation

Function

Promotes cell survival. Suppresses apoptosis.

Subcellular Localization

Mitochondrion {ECO:0000250}. Nucleus membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in multiple embryonic tissues. Restricted to the ovary and testis in adult mice.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0042981	regulation of apoptotic process
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005829	cytosol
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031965	nuclear membrane