Version 5.4
| Mus musculus Protein: Oxct2a | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-185406.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Oxct2a | ||||||||
| Protein Name | 3-oxoacid CoA transferase 2A | ||||||||
| Synonyms | Oxct; Oxct2; Scot; Scot-t1; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000099700 | ||||||||
| InnateDB Gene | IDBG-185404 (Oxct2a) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). Probably play and important roles in the energy metabolism of spermatozoa. {ECO:0000250}. | ||||||||
| Subcellular Localization | Mitochondrion {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1891061 | ||||||||
| InterPro |
IPR004165
Coenzyme A transferase family I IPR012791 3-oxoacid CoA-transferase, subunit B IPR012792 3-oxoacid CoA-transferase, subunit A IPR014388 3-oxoacid CoA-transferase |
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| PFAM |
PF01144
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| PRINTS | |||||||||
| PIRSF |
PIRSF000858
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| SMART |
SM00882
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9JJN4 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 64059 | ||||||||
| UniGene | Mm.270287 | ||||||||
| RefSeq | NP_071316 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Oxct2a | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18617 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB022180 AB105454 AK077075 AL606917 BC137887 BC137888 | ||||||||
| GenPept | AAI37888 AAI37889 BAA97654 BAC36595 BAC87737 CAM46094 | ||||||||