Version 5.4
Mus musculus Protein: Ibsp
Summary
InnateDB Protein IDBP-185415.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ibsp
Protein Name integrin binding sialoprotein
Synonyms BSP; BSP II; Bsp2; BSPII;
Species Mus musculus
Ensembl Protein ENSMUSP00000031246
InnateDB Gene IDBG-185413 (Ibsp)
Protein Structure
UniProt Annotation
Function Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001503 ossification
GO:0001649 osteoblast differentiation
GO:0007155 cell adhesion
GO:0030198 extracellular matrix organization
GO:0031214 biomineral tissue development
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
GO:0031988 membrane-bounded vesicle
Protein Structure and Domains
PDB ID MGI:96389
InterPro IPR008412 Bone sialoprotein II
PFAM PF05432
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61711
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 15891
UniGene Mm.4987
RefSeq NP_032344
MGI ID
MGI Symbol Ibsp
OMIM
CCDS CCDS19485
HPRD
IMGT
EMBL AK132371 BC045143 CH466529 L20232 L23801
GenPept AAA21726 AAA37326 AAH45143 BAE21132 EDL20226

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca