InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bmp5

Summary

InnateDB Protein

IDBP-185559.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bmp5

Protein Name

bone morphogenetic protein 5

Synonyms

AU023399; se;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000012281

InnateDB Gene

IDBG-185557 (Bmp5)

Protein Structure

UniProt Annotation

Function

Induces cartilage and bone formation.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0070700	BMP receptor binding

Biological Process

GO:0001501	skeletal system development
GO:0001503	ossification
GO:0003323	type B pancreatic cell development
GO:0007389	pattern specification process
GO:0008285	negative regulation of cell proliferation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010894	negative regulation of steroid biosynthetic process
GO:0030539	male genitalia development
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0040007	growth
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050679	positive regulation of epithelial cell proliferation
GO:0051216	cartilage development
GO:1900006	positive regulation of dendrite development
GO:2000065	negative regulation of cortisol biosynthetic process
GO:2000105	positive regulation of DNA-dependent DNA replication