InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tekt3

Summary

InnateDB Protein

IDBP-185577.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tekt3

Protein Name

tektin 3

Synonyms

4933407G07Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042063

InnateDB Gene

IDBG-185575 (Tekt3)

Protein Structure

UniProt Annotation

Function

Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). Required for progressive sperm mobility. {ECO:0000250, ECO:0000269PubMed:18951373}.

Subcellular Localization

Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed preferentially in testis. Expressed predominantly in late pachytene spermatocytes and early round spermatids. Expressed in flagellar accessory structures. {ECO:0000269PubMed:14735490, ECO:0000269PubMed:18951373}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0030317	sperm motility
GO:0060271	cilium morphogenesis
GO:0080154	regulation of fertilization

Cellular Component

GO:0002080	acrosomal membrane
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0036126	sperm flagellum
GO:0070062	extracellular vesicular exosome