InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gstm7

Summary

InnateDB Protein

IDBP-185758.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gstm7

Protein Name

glutathione S-transferase, mu 7

Synonyms

0610005A07Rik; AI894236; Cd203c;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004137

InnateDB Gene

IDBG-185756 (Gstm7)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0042803	protein homodimerization activity
GO:0043295	glutathione binding

Biological Process

GO:0006749	glutathione metabolic process
GO:0008152	metabolic process
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0018916	nitrobenzene metabolic process
GO:0042178	xenobiotic catabolic process
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070458	cellular detoxification of nitrogen compound
GO:0071313	cellular response to caffeine

Cellular Component

GO:0005737	cytoplasm
GO:0016529	sarcoplasmic reticulum
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1915562

InterPro

IPR003081 Glutathione S-transferase, Mu class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM