Version 5.4
Mus musculus Protein: Slc2a3
Summary
InnateDB Protein IDBP-185766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc2a3
Protein Name solute carrier family 2 (facilitated glucose transporter), member 3
Synonyms AA408729; AL023014; AL024341; AU040424; C78366; Glut-3; Glut3;
Species Mus musculus
Ensembl Protein ENSMUSP00000032476
InnateDB Gene IDBG-185764 (Slc2a3)
Protein Structure
UniProt Annotation
Function Facilitative glucose transporter. Probably a neuronal glucose transporter.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
GO:0033300 dehydroascorbic acid transporter activity
GO:0055056 D-glucose transmembrane transporter activity
Biological Process
GO:0015758 glucose transport
GO:0055085 transmembrane transport
GO:0070837 dehydroascorbic acid transport
Cellular Component
GO:0002080 acrosomal membrane
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95757
InterPro IPR002945 Glucose transporter, type 3 (GLUT3)
IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF00083
PF07690
PRINTS PR01192
PR00171
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P32037
PhosphoSite PhosphoSite-P32037
TrEMBL Q3TPL8
UniProt Splice Variant
Entrez Gene 20527
UniGene Mm.484362
RefSeq NP_035531
MGI ID
MGI Symbol Slc2a3
OMIM
CCDS CCDS20502
HPRD
IMGT
EMBL AC131715 AC163108 AK155997 AK164286 BC034122 BC058811 CH466523 M75135 U11844 U11845 U11846 U11848 U11849 U11850 U11851 U11852 U11853 X61093
GenPept AAA37704 AAB60666 AAH34122 AAH58811 BAE33537 BAE37718 CAA43406 EDK99695

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca