Version 5.4
Mus musculus Protein: Krt7
Summary
InnateDB Protein IDBP-185785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt7
Protein Name keratin 7
Synonyms D15Wsu77e; K7; Krt2-7;
Species Mus musculus
Ensembl Protein ENSMUSP00000069900
InnateDB Gene IDBG-185783 (Krt7)
Protein Structure
UniProt Annotation
Function Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in most simple epithelia tested including liver, lactating mammary gland, lung, kidney, stomach, duodenum, colon, oviduct, uterus, pancreas, epididymis, prostate, preputial gland and mesothelium, and in most stratified epithelia tested including dorsal skin, paw/toe, tail, tongue, cervix, forestomach, and bladder. Also expressed in Henle layer of the inner root sheath of whisker follicle. {ECO:0000269PubMed:12359226}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005882 intermediate filament
GO:0045095 keratin filament
Protein Structure and Domains
PDB ID MGI:96704
InterPro IPR001664 Intermediate filament protein
IPR003054 Keratin, type II
IPR009053 Prefoldin
PFAM PF00038
PRINTS PR01276
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCV7
PhosphoSite PhosphoSite-Q9DCV7
TrEMBL D3Z6N5
UniProt Splice Variant
Entrez Gene 110310
UniGene Mm.487410
RefSeq NP_149064
MGI ID
MGI Symbol Krt7
OMIM
CCDS CCDS27851
HPRD
IMGT
EMBL AC157583 AF509888 AF509890 AK002434 AK137217 AK146914 BC030403
GenPept AAH30403 AAN64032 AAN64034 BAB22099 BAE23275 BAE27526

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca