Version 5.4
| Homo sapiens Protein: ADAM18 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-18579.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ADAM18 | ||||||||
| Protein Name | ADAM metallopeptidase domain 18 | ||||||||
| Synonyms | ADAM27; tMDCIII; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000265707 | ||||||||
| InnateDB Gene | IDBG-18575 (ADAM18) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed specifically in testis. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001590
Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF01421
PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||
| SMART |
SM00050
SM00608 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9Y3Q7 | ||||||||
| PhosphoSite | PhosphoSite-Q9Y3Q7 | ||||||||
| TrEMBL | Q0VAI3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 8749 | ||||||||
| UniGene | Hs.127930 | ||||||||
| RefSeq | NP_055052 | ||||||||
| HUGO | HGNC:196 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS6113 | ||||||||
| HPRD | 07469 | ||||||||
| IMGT | |||||||||
| EMBL | AC109633 AC136365 AJ133004 AK313961 AY358321 BC034624 BC070279 BC121045 BC121046 | ||||||||
| GenPept | AAH34624 AAH70279 AAI21046 AAI21047 AAQ88687 BAG36677 CAB40812 | ||||||||